Journal/Ingredients & evidence
The complete evidence guide

The research behind our Hydroxyethyl Urea Body Cream

What urea does for rough, dry skin, why our cream uses hydroxyethyl urea instead, what 2% panthenol and three other humectants add, and what the research does and doesn't prove.

Elurelia EditorialUpdated 26 September 202614 min read9 references
Photo 40 · Hero · The green body cream bottle beside a generous swirl of white cream and a halved cucumber and bergamot, soft daylight. No people. · 2400×1030 · 21:9
Key takeaways
1Urea is one of the best-studied ingredients for dry skin. At 10% and above it also softens thick, rough skin. 2Our cream contains hydroxyethyl urea, not plain urea. It is a related humectant with a lighter feel. The urea research doesn't transfer to it directly, and we say so. 32% panthenol has human evidence. Creams with 1% and 5% panthenol reduced water loss through the skin in a 30-day study. 4Four humectants, one light organic oil. Hydroxyethyl urea, glycerin, sodium PCA and hyaluronic acid, with sunflower seed oil. 5It is scented, with ten declared allergens. Including bergamot and bitter orange oils. We name them all.

Rough elbows, dry shins and hard heels are some of the most common skin complaints there are, and some of the easiest to improve. The ingredient most dermatologists reach for first is urea. Our body cream contains a close relative of it, and this guide explains exactly what that means.

We go through what urea does, why our cream uses hydroxyethyl urea, what the 2% panthenol and the other humectants add, and where the evidence is strong or thin. If you only want the product, the body cream page has everything in one place. If you are choosing between our two body creams, this short guide helps.

01Why skin gets rough and dry

The outer layer of your skin is made of flat, dead cells that are shed and replaced all the time. To stay soft and flexible, this layer needs water, and it holds that water with a mix of small molecules called natural moisturising factor, or NMF, and with lipids between the cells.

When NMF and lipids run low, the outer layer dries out. Dry cells don't shed properly, so they pile up into rough, flaky, sometimes greyish patches. Elbows, knees, shins and heels are hit hardest, because they have fewer oil glands and more friction. Winter heating, hot showers, strong soaps and age all make it worse.

A good body cream does two things: it puts water-binding molecules back into the outer layer, and it adds lipids that slow water loss. Urea, and ingredients like it, do the first job.

02What urea does in the skin

Urea is part of the skin's own NMF. It is a small, water-loving molecule that attracts and holds water in the outer layer. Applied in a cream, it tops up that supply. At higher concentrations it also loosens the bonds between the dead cells that make rough skin feel thick, which helps them shed.

This is why urea has been used in dermatology for decades, from gentle everyday lotions to strong creams for calluses and thickened nails.

03Urea by strength

Urea strength Main effect Typical use
Up to about 10% Moisturising: draws water into the skin Everyday dry skin
10% to 20% Moisturising and softening rough skin Rough elbows, knees, heels
20% to 40% Softens and loosens thick skin Calluses, very thick heels
40% and above Breaks down thick keratin Thickened nails, under medical advice

These bands are approximate; reviews of urea describe a gradual shift from moisturising to softening as the concentration rises. We explain them in more detail in 5%, 10% or 40% urea: how much do you need?

Original sources
  1. Celleno L. Topical urea in skincare: A review. Dermatol Ther 31(6):e12690, 2018. Read the source

04The human evidence for urea

Urea moisturisers

Evidence: human trial
StudyLodén, 1996. Archives of Dermatological Research.
What was testedVolunteers applied urea moisturisers or urea-free moisturisers to normal skin for 3, 10 and 20 days, and their skin was then exposed to an irritant detergent (sodium lauryl sulfate).
What they foundAfter 20 days, the urea creams lowered water loss through the skin and reduced irritant reactions. After just three applications, skin reacted less to the irritant and held more water. The urea-free creams didn't change water loss or irritant reactions.
What it doesn't proveIt tested plain urea. Our cream contains hydroxyethyl urea, a different molecule, so this result doesn't transfer directly.
In our creamHydroxyethyl urea, fourth on the list, not plain urea.
Original sources
  1. Lodén M. Urea-containing moisturizers influence barrier properties of normal skin. Arch Dermatol Res 288(2):103–107, 1996. Read the source

05Hydroxyethyl urea, and why we're telling you

Hydroxyethyl urea is urea with a small hydroxyethyl group attached. That change makes it a strong humectant with a lighter, less sticky feel than glycerin, and it is used in body lotions for exactly that reason.

It is not the same molecule as urea. The decades of research on urea, especially its softening effect at 10% and above, were done on plain urea. We found only limited published research on hydroxyethyl urea, most of it from the companies that make it.

Hydroxyethyl urea

Evidence: maker's data
StudyLanda et al., 2009. Cosmetics & Toiletries.
What was testedLab and panel tests comparing hydroxyethyl urea with glycerin for water uptake, water retention, moisturisation and skin feel.
What they foundHydroxyethyl urea moisturised about as well as glycerin, with less tackiness, greasiness and gloss.
What it doesn't proveIt was published in a trade journal by scientists at the company that made the ingredient, and it isn't an independent trial. It doesn't show that hydroxyethyl urea softens thick skin the way plain urea does.
In our creamHydroxyethyl urea is the fourth ingredient.
Original sources
  1. Landa P. et al. Glycerin and hydroxyethyl urea: comparing two skin moisturizers. Cosmetics & Toiletries, 2009. Read the source
Why the name mattersMany body creams say "urea" on the front. Ours contains hydroxyethyl urea, so that is what we call it. If you need plain urea at 10% or more for very thick or cracked skin, ask a pharmacist.

06How we rate the evidence

Label What it means
Human trial People used it and it was measured, ideally against a comparison.
Review A summary of earlier studies.
Maker's data Tests run or published by the company that sells the ingredient.
Lab Cells or ingredients in a lab. Mechanism, not results on skin.

None of these studies tested our body cream. They tested ingredients, usually in other products. We use them to explain why each ingredient is there, and we say what each one doesn't prove.

Hydroxyethyl Urea Body Cream Four humectants and 2% panthenol for rough, dry skin. 60-Day Promise on your first order, conditions apply.

07Panthenol (pro-vitamin B5)

Panthenol is the second hero ingredient and, at 2%, one of the few in the cream with a stated percentage. In the skin it is converted to pantothenic acid, vitamin B5, which cells use in making lipids. It is also a humectant in its own right.

Panthenol

Evidence: human trial
StudyCamargo, Gaspar & Maia Campos, 2011. Journal of Cosmetic Science.
What was testedHealthy volunteers applied creams with 0.5%, 1% or 5% panthenol, a plain base or nothing to the forearm daily for 30 days. A second test applied the creams to skin that had just been washed with a detergent (sodium laureth sulfate).
What they foundThe 1% and 5% creams significantly reduced water loss through the skin after 30 days. On detergent-washed skin, the panthenol creams reduced water loss two hours after application.
What it doesn't proveIt was a forearm study of different creams, and it measured water loss, not roughness. Our 2% sits between the two concentrations that worked; it wasn't tested itself.
In our cream2% panthenol, seventh on the list.
Original sources
  1. Camargo F.B. Jr, Gaspar L.R., Maia Campos P.M. Skin moisturizing effects of panthenol-based formulations. J Cosmet Sci 62(4):361–370, 2011. Read the source
  2. Proksch E. et al. Topical use of dexpanthenol: a 70th anniversary article. J Dermatolog Treat 28(8):766–773, 2017.

A review marking seventy years of dexpanthenol use summarised a broad body of research on its moisturising and barrier-supporting effects, much of it on medicinal creams at 5%. That review is useful background. It doesn't test our cream.

08Glycerin

Glycerin, the third ingredient, is the most studied humectant in skincare. A detailed review concluded that glycerol improves hydration of the outer layer and supports barrier function. It works alongside hydroxyethyl urea: both pull water into the skin, and hydroxyethyl urea reduces some of the stickiness a high glycerin level can bring.

Original sources
  1. Fluhr J.W., Darlenski R., Surber C. Glycerol and the skin: holistic approach to its origin and functions. Br J Dermatol 159(1):23–34, 2008.

09Sodium PCA

Sodium PCA

Evidence: review
StudyClar & Fourtanier, 1981. International Journal of Cosmetic Science.
What was testedA review of research on PCA (pyrrolidone carboxylic acid), the largest single part of the skin's own natural moisturising factor.
What they foundCreams with at least 2% PCA or its sodium salt improved dry skin.
What it doesn't proveIt is an older review, and much of it is the authors' own work. Our percentage isn't known.
In our creamSodium PCA, eleventh on the list.
Original sources
  1. Clar E.J., Fourtanier A. Pyrrolidone carboxylic acid and the skin. Int J Cosmet Sci 3(3):101–113, 1981.

10A little hyaluronic acid

Sodium hyaluronate, a form of hyaluronic acid, sits near the end of the list. It holds water on the surface of the skin and adds to the smooth feel. In a body cream at this position, we count it as a finishing touch rather than a main active.

11Sunflower seed oil

The second ingredient is organic sunflower seed oil, a light oil rich in linoleic acid, a fatty acid the skin uses to build its barrier lipids.

Sunflower seed oil

Evidence: human trial
StudyDanby et al., 2013. Pediatric Dermatology.
What was testedAdults without skin disease applied sunflower seed oil to one forearm and olive oil to the other, twice a day for four weeks.
What they foundSunflower seed oil preserved the skin barrier and improved hydration. Olive oil weakened the barrier.
What it doesn't proveIt was a small study of the pure oils on the forearm, not a cream.
In our creamOrganic sunflower seed oil, second on the list.
Original sources
  1. Danby S.G. et al. Effect of olive and sunflower seed oil on the adult skin barrier: implications for neonatal skin care. Pediatr Dermatol 30(1):42–50, 2013.

12The emollients: why it absorbs fast

Rich body creams often feel greasy because they rely on heavy oils and waxes. This one uses lighter emollients: two plant triglycerides (caprylic/capric triglyceride and a caprylic/capric/myristic/stearic blend) and dicaprylyl carbonate, which spreads easily and leaves a dry, silky finish. Cetearyl alcohol, a fatty alcohol from plant oils, thickens the cream; it is not a drying alcohol.

The result is a cream that feels rich going on and absorbs quickly, so you can get dressed straight away.

13Vitamin E and a vitamin C ester

Tocopherol (vitamin E) and ascorbyl palmitate (an oil-soluble form of vitamin C) are near the end of the list. Their main job is to protect the sunflower oil from going rancid. We don't market this cream on vitamin C or E, because at these levels they are there for the formula, not for your skin.

14The scent, and all ten allergens

The cream has a fresh cucumber and citrus scent from Parfum and three essential oils: bergamot, bitter orange and ylang-ylang. In 2023 the EU made its list of fragrance allergens that must be named on labels much longer, and essential oils such as bergamot, bitter orange and ylang-ylang are now on it by name. The new rules apply to products placed on the market from July 2026.

So this cream declares ten allergens: Benzyl Salicylate, Limonene, bergamot peel oil, bitter orange peel oil, Citral, Linalool, Linalyl Acetate, Pinene, ylang-ylang oil, and Benzyl Alcohol, which is also used as a preservative. Most people use scented body creams without a problem. If fragrance is a trigger for you, choose our Sensitive Skin Body Cream, which declares five, or a fragrance-free product.

Original sources
  1. Commission Regulation (EU) 2023/1545 of 26 July 2023 amending Regulation (EC) No 1223/2009 as regards labelling of fragrance allergens in cosmetic products. Official Journal of the European Union L 188, 2023. Read the source

15Citrus oils and sunlight

Bergamot and some other citrus peel oils can contain natural compounds that make skin react more strongly to sunlight. Many cosmetic grades have these compounds removed, and EU rules limit them. We have asked for confirmation of the grade used in our cream. Until we have it, our advice is simple: apply it in the evening, or let it absorb fully before strong sun, and skip sunbeds straight after applying.

16Where to use it

Use it anywhere on the body that feels dry: legs, arms, back of the hands, and especially elbows, knees and heels. On very rough spots, apply a little extra and massage it in. It is not made for the face; the scent and essential oils make it a poor choice there.

Don't apply it to cracked, bleeding or broken skin. If you have diabetes and dry or cracked feet, speak to your doctor or podiatrist before using any foot cream.

17How to use it for best results

  • Wash with a mild cleanser and lukewarm water. Our Face & Body Cleanser suits it.
  • Pat dry, leaving the skin slightly damp. Humectants work best when there is water to hold on to.
  • Massage a generous amount over dry areas, with extra on elbows, knees and heels.
  • Repeat once or twice a day. Rough skin improves with daily use and comes back when you stop.

Used daily over the whole body, a 280 ml bottle lasts around four weeks. On elbows, knees and heels only, it lasts much longer.

18When to see a doctor instead

A body cream is for everyday dry, rough skin. See a doctor or pharmacist if your skin cracks or bleeds, itches badly, has red, inflamed patches, or doesn't improve after a few weeks of daily moisturising. Those can be signs of eczema, psoriasis or another condition that needs proper care.

Hydroxyethyl Urea Body Cream After the shower, every day. 60-Day Promise on your first order, conditions apply.

19Body skin through the year

Body skin is often at its driest in winter, when cold air outside and heating inside pull water from the skin, and people take longer, hotter showers. Many people find their shins and forearms flake from November to March and improve in summer. Others find the opposite: sun, sea water, chlorine and air conditioning dry them out in July.

The fix is the same in both cases: keep showers lukewarm and short, moisturise every day rather than when you remember, and use a little more on the areas that always get rough. A cream that absorbs fast makes the daily habit easier to keep.

20Three myths about dry body skin

"Scrubbing will fix rough skin." Scrubbing lifts flakes for a day, but it doesn't replace the water and lipids the skin is missing, and overdoing it makes dryness worse. Moisturising daily does more.

"Oil is the best moisturiser." Oils soften the surface and slow water loss, but they don't add water. Rough skin usually needs humectants as well, which is why this cream combines both.

"If it stings, it's working." Stinging means the skin is irritated or broken. Stop, and see a pharmacist if it continues.

21Who it suits, and who should skip it

It suits you if your elbows, knees, heels or shins feel rough and dry; you want a body cream that absorbs fast; you like a fresh citrus scent; and you want every ingredient and allergen named.

Skip it, or check first, if you need a fragrance-free product; you want plain urea at 10% or more; you react to citrus oils or will be in strong sun straight after applying; or you have broken skin or a skin condition.

22What it adds up to

This is a fast-absorbing body cream built around hydration. It combines four humectants, hydroxyethyl urea, glycerin, sodium PCA and hyaluronic acid, with 2% panthenol, which has good human evidence for reducing water loss, and a light organic sunflower oil. It is scented, with ten declared allergens.

It is not a plain urea cream, and we don't pretend it is. The strongest urea evidence doesn't apply to it. What it offers is a pleasant, effective daily moisturiser for rough, dry skin, with an honest label. If that is what you need, it is a good choice.

23Your questions, answered

Is hydroxyethyl urea the same as urea?

No. It is urea with a small hydroxyethyl group attached. It is a strong humectant with a lighter feel, but the research on plain urea doesn't transfer to it directly.

How much urea does this cream contain?

It contains hydroxyethyl urea, not plain urea. The exact percentage isn't confirmed to us, so we don't state one.

What does 2% panthenol do?

Panthenol turns into vitamin B5 in the skin and helps it hold water. In a 30-day study, creams with 1% and 5% panthenol reduced water loss through the skin.

Can I use it on my face?

It is made for the body. The scent and essential oils make it a poor choice for the face.

Can I use it on cracked heels?

On dry, rough heels, yes. On cracks or broken skin, no: ask a pharmacist or doctor.

Is it fragrance free?

No. It declares ten allergens, including bergamot, bitter orange and ylang-ylang oils.

Is it vegan?

Yes. It is also gluten free and nut free.

Does the 60-Day Promise apply?

Yes, on your first order, conditions apply. The full terms are on our 60-Day Promise page.

Hydroxyethyl Urea Body Cream Honest hydration for rough, dry skin. 60-Day Promise on your first order, conditions apply.

This article is for general information and isn't medical advice. Cosmetic products: all claims describe the appearance and feel of skin.

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